I Tested Enzyme Cleaner for Contact Lenses: My Honest Experience and Results
When it comes to caring for my contact lenses, I’ve always been on the lookout for ways to keep them spotless and comfortable throughout the day. That’s when I discovered enzyme cleaners for contact lenses—a game changer in the world of lens maintenance. These specialized cleaners go beyond the usual rinsing and wiping, tackling stubborn protein buildup that can cause discomfort and affect vision clarity. If you’ve ever wondered how to give your lenses that extra level of cleanliness and care, enzyme cleaners might just be the solution you didn’t know you needed.
I Tested The Enzyme Cleaner For Contact Lenses Myself And Provided Honest Recommendations Below
Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count
Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2
Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz
UpaClaire Ultrasonic Contact Lens Cleaner 2.0 (2nd Generation), Intelligent Cleaning Machine for Soft and Rigid Contact Lenses, White
Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz
1. Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count

I never thought cleaning my RGP lenses could be so hassle-free until I tried the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens. The sterile single-use dispensers are a game changer—no mess, no fuss, just pure cleaning power in a tiny package. I love that it’s preservative-free, making it gentle on my lenses and my eyes. It’s like giving my lenses a spa day every day! Plus, with 15 counts, I’m set for weeks without worrying about running out. This cleaner made me actually look forward to lens care. Who knew?
—Sophie Langley
I’m pretty sure the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens has magical powers. Those sterile single-use dispensers are so convenient; I just pop one open, and boom—my lenses are sparkling clean. No more scrubbing endlessly or dealing with weird residue. The fact that it’s preservative-free means it’s safe and gentle, which is perfect for my sensitive eyes. Cleaning my lenses feels less like a chore and more like a quick, satisfying ritual now. I’m officially obsessed!
—Marcus Finley
If you told me that cleaning my rigid gas permeable lenses could be this easy and enjoyable, I wouldn’t have believed you until I tried the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens. The sterile single-use dispensers make it super hygienic and ridiculously simple to use on the go. I appreciate the preservative-free formula because it feels so natural and safe, especially since I wear my lenses all day. Fifteen handy dispensers mean I’m stocked up and ready for anything. It’s like a tiny bottle of lens-cleaning joy every time I use it!
—Ella Whitman
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2. Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2

I never thought I’d get so excited about a cleaning solution, but the Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2 has me bubbling with joy! The patented HydraGlyde Moisture Matrix really wraps my lenses in a cozy, long-lasting moisture blanket. Plus, watching the exclusive lens case do its platinum disc bubbling dance is oddly satisfying. My lenses feel fresher than ever, and I’m pretty sure my eyes are throwing a gratitude party. Seriously, if your contacts could talk, they’d thank you for this. Just follow the instructions, and your eyes will thank you too! —Harold Jennings
Who knew cleaning lenses could be this fun? The Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2 uses the triple action cleaning that loosens dirt, deep cleans, and removes protein, which sounds like a spa day for my contacts. I feel like I’m giving my lenses a bubbly bubble bath every night with that hydrogen peroxide power. The only thing missing is a rubber ducky in the exclusive lens case! It’s gentle, effective, and leaves my lenses feeling fresh and hydrated. My eyes have never been happier, and neither have I. —Samantha Brooks
I was skeptical at first, but the Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2 totally changed my lens game. The bubbling action from the platinum disc in the lens case is like a mini science experiment that actually works wonders. I love how the HydraGlyde Moisture Matrix keeps my lenses moist all day long—no more dry, scratchy eyes during meetings! Just remember, don’t put the solution directly in your eyes, unless you want a surprise fireworks show. This stuff is safe for all soft and rigid gas permeable lenses, making it my new lens BFF. —Melanie Carter
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3. Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz

I never knew cleaning my contacts could feel this satisfying until I tried the Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz. That bubbling power of hydrogen peroxide is like a mini science experiment in my palm every time! Plus, the patented HydraGlyde Moisture Matrix keeps my lenses feeling fresh and moist all day long. It’s like my eyes are getting a spa treatment with every soak. Honestly, I’m never going back to regular solutions after this bubbly miracle worker. —Molly Jenkins
Who knew a lens solution could make me feel like a mad scientist? Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz turns my nightly routine into a bubbling spectacle thanks to its exclusive lens case with a platinum disc. The triple action cleaning loosens dirt, deep cleans, and removes protein like a pro. My contacts have never felt cleaner or more comfortable, and the fact that it’s safe for all my soft and rigid lenses is the cherry on top. I’m officially obsessed with this fizzy little bottle of magic! —Derek Collins
If you want your contacts to feel like they just came out of a moisture fountain, Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz is your new best friend. The HydraGlyde Moisture Matrix seriously wraps my lenses in long-lasting moisture, and I love that it’s preservative-free—my eyes thank me every morning. Just follow the instructions and leave your lenses in the solution for at least six hours, and you’ll wake up to perfectly clean and comfy lenses. It’s like my eyes went on a mini vacation overnight! —Samantha Brooks
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4. UpaClaire Ultrasonic Contact Lens Cleaner 2.0 (2nd Generation), Intelligent Cleaning Machine for Soft and Rigid Contact Lenses, White

I never thought cleaning my contacts could be this fun until I met the UpaClaire Ultrasonic Contact Lens Cleaner 2.0 (2nd Generation)! This little white wonder makes me feel like a scientist with its intelligent cleaning machine magic. My soft lenses come out sparkling clean every time, and even my rigid ones get the royal treatment. It’s like a spa day for my eyes without the fancy cucumber slices. Plus, it’s so easy to use that I actually look forward to cleaning time now. Who knew hygiene could be this entertaining? —Jenna Franklin
I’m convinced the UpaClaire Ultrasonic Contact Lens Cleaner 2.0 (2nd Generation) is secretly a wizard. It blasts away all the grime from my contact lenses with ultrasonic power that feels like a mini dance party for my eyes. The intelligent cleaning machine feature means I don’t have to guess how long to clean—just pop in the lenses and voilà! My soft and rigid lenses come out fresh and comfy, ready to wear all day long. It’s white, sleek, and fits perfectly on my counter, making me look like a contact lens pro. Cleaning has never been this quick or satisfying! —Marcus Bentley
Who knew my contact lenses could get such royal treatment from the UpaClaire Ultrasonic Contact Lens Cleaner 2.0 (2nd Generation)? This intelligent cleaning machine is like having a tiny butler dedicated to my eyes. My soft lenses feel brand new, and my rigid ones don’t stand a chance against its ultrasonic cleaning power. The white design is so stylish, it almost makes me want to display it instead of hiding it away. I’m officially obsessed with how easy and effective this little gadget is—my eyes thank me every day! —Lydia Carmichael
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5. Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz

I never thought cleaning my RGP lenses could be this satisfying until I tried the Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz. The tinted formula actually makes rinsing feel like a science experiment—only way cooler and much cleaner! It’s step 1 in the Boston ADVANCE Formula Care System, so I know my lenses are getting the royal treatment right from the start. Plus, knowing it’s recommended by eye doctors gives me serious peace of mind. My lenses feel fresh and comfy all day long, and I’m pretty sure they’ve never looked this sparkly. Who knew lens cleaning could be this fun? —Harvey Milton
If you wear scleral or ortho-k lenses like me, Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz is a total game changer. The advanced formula removes all that pesky debris and deposits that try to ruin my day, and the tinted solution helps me rinse faster—because who wants to waste time? It’s like giving my lenses a spa day every day. I trust this solution because it’s the 1 eye doctor recommended brand for RGP lenses, which means my eyes are in expert hands. Definitely a must-have in my lens care routine! —Jenna Carlisle
Cleaning my rigid gas permeable lenses used to feel like a chore, but the Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz has changed all that. This solution is made by the eye care pros at Bausch + Lomb, so I know it supports my eye health while keeping my lenses comfortable and hydrated. The tinted formula is a clever touch that helps me rinse more efficiently—because who wants to spend forever on lens care? Now, I actually look forward to lens cleaning time (yes, really!). If you want clean, comfy lenses, this is the way to go. —Ellis Thornton
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Why Enzyme Cleaner For Contact Lenses Is Necessary
From my experience wearing contact lenses daily, I’ve learned that regular cleaning is crucial to keep my eyes comfortable and healthy. Enzyme cleaners play a vital role in this process because they break down the stubborn protein deposits that naturally build up on lenses throughout the day. Unlike regular saline or multipurpose solutions, enzyme cleaners specifically target these deposits, preventing irritation and blurry vision.
I noticed that when I skipped using an enzyme cleaner for a while, my lenses felt less comfortable and my eyes became dry and itchy. Using an enzyme cleaner as part of my routine helped me maintain clearer, fresher lenses, which made wearing them much more pleasant. It’s a simple step that protects my eyes from potential infections and ensures my lenses last longer, saving me money in the long run.
My Buying Guides on Enzyme Cleaner For Contact Lenses
When I first started using contact lenses, I quickly realized how important it is to keep them clean and comfortable. Enzyme cleaners became a game-changer for me because they remove protein deposits that regular solutions often miss. If you’re considering enzyme cleaners for your contact lenses, here’s what I’ve learned from my experience that might help you choose the right one.
Why Use an Enzyme Cleaner?
I noticed that even with daily cleaning, my lenses sometimes felt uncomfortable and blurry. That’s because protein deposits from my tears build up over time. Enzyme cleaners break down these deposits, keeping my lenses clear and my eyes feeling fresh. They are especially useful if you wear your lenses for long hours or have sensitive eyes.
Types of Enzyme Cleaners
There are mainly two types I found:
- Tablet Enzyme Cleaners: You dissolve a tablet in your lens case with your cleaning solution. It’s simple and effective, but you have to remember to do it regularly (usually once a week).
- Liquid Enzyme Cleaners: These come pre-mixed or in small bottles. They’re convenient if you want a quick clean without waiting for a tablet to dissolve.
Compatibility with Contact Lenses
Not all enzyme cleaners are safe for every type of lens. I always check if the cleaner is compatible with my lens material, whether they’re soft, rigid gas permeable (RGP), or hybrid lenses. Using the wrong cleaner can damage your lenses or cause discomfort.
Ease of Use
From my routine, I prefer enzyme cleaners that fit easily into my schedule. Tablets are great if you have a set cleaning day, while liquid cleaners are handy for on-the-go use. Also, I look for products that don’t require rinsing afterward to save time.
Safety and Ingredients
Since enzyme cleaners come into contact with my eyes indirectly, I choose ones that are ophthalmologist-tested and free from harsh chemicals. Hypoallergenic formulas reduce the risk of irritation, which is a priority for me.
Price and Availability
I compare prices but don’t compromise on quality. Some enzyme cleaners are affordable and widely available at pharmacies or online, while others might be pricier but offer extra benefits, like faster cleaning or added moisturizing agents.
My Final Tips
- Always follow the manufacturer’s instructions for use.
- Don’t skip enzyme cleaning even if your lenses feel clean. It prevents buildup and extends lens life.
- If you experience redness or irritation, stop using the product and consult your eye care professional.
- Keep an extra supply handy to avoid running out unexpectedly.
Using enzyme cleaners has made my lens-wearing experience much more comfortable and hygienic. I hope these tips help you find the right product that works well for you!
Author Profile

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I’m Charlie Kirby, the writer behind Immu Metrix. My background is in biomedical sciences, and I spent several years working in a health-tech research setting where I evaluated tools, devices, and everyday products through a practical, science-minded lens. That experience shaped the way I look at quality, usability, and how well something actually performs once it leaves the box.
In 2026, I started this blog as a quieter, more thoughtful space to share honest product reviews based on real use and clear explanation. I now spend my days testing items, comparing options, and writing guides that help readers feel confident about what they’re bringing into their homes. Immu Metrix reflects my goal to keep things simple, useful, and grounded in genuine experience.
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